Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp59 | Bone and Osteoporosis | ECE2018

Thirty-one men and women with145 spontaneous vertebral fractures after denosumab discontinuation: a single center observational study

Elena Gonzalez Rodriguez , St Delphine , Aubry-Rozier Berengere , Olivier Lamy

Denosumab discontinuation (DD) induces an increase of B-crosslaps above baseline values for two years, and a decrease of BMD values. This rebound effect is associated with spontaneous clinical vertebral fractures (SCVF) in close to 15% of patients considering a follow-up of 2 years without taking another osteoporosis treatment. We report the clinical characteristics of 31 patients evaluated at our center from July 2015 to January 2018.Results: Thirty wom...